Jocelyne DiRuggiero
NetBet sport
Contact Information
- [email protected]
- 235 Levi Hall
- 410-516-8498 | Lab 410-516-7744
- Group/Lab Website
netbet casino appMolecular microbial ecology of extremophiles; molecular mechanisms of stress response
Jocelyne DiRuggiero is an associate professor in the netbet online sports bettingDepartment of Biology and holds an appointment in the Department of Earth and Planetary Sciences. She received her PhD from the University Claude Bernard in Lyon, France. Her research focuses on the mechanisms of stress response in the Archaea and on the microbial ecology of extreme environments.
From a single-cell as a microcosm to complex microbial consortia that inhabit extreme environments, our research probes how microorganisms adapt and respond to environmental stresses. Our research spans the fields of molecular biology, metagenomics, microbial ecology, and planetary science. We use archaeal model systems in the lab and do fieldwork in extreme deserts around the world.
Archaea are abundant in extreme environments, presenting an opportunity to gain insights into molecular adaptations to hostile habitats. Archaea are evolutionarily closer to Eukarya as emphasized by the recent discovery of the Asgard archaeal superphylum. This close NetBet sportevolutionary relationship between the archaeal and eukaryal domains is expressed by similarities of central dogma processes (replication, transcription, and translation) and an expected complexity in the Archaea. We thus stand to discover novel mechanisms and processes by studying the molecular biology of Archaea. We use the haloarchaeon Haloferax volcanii as a model to investigate regulatory mechanisms, at the post-transcriptional and translational level, in response to environmental stressors
Deserts and hypersaline environments represent the dry limits for life on Earth. These are fragile ecosystems and, as such, are unique model systems to study the effect of climate change on communities and ecosystems. Under the harsh conditions of hyper-arid deserts, microorganisms find refuge inside rocks as a survival strategy. We use these endolithic microbial communities from the Atacama, Namib, Negev, and Mojave Deserts and the Dry Valleys of Antarctica to address fundamental questions in microbial ecology.
Our research is directly related to Astrobiology. Visit the Institute for Planets and Life web site
Atacama Desert, Chile
Molecular Biology of Archaea
Gelsinger D.R., R. Reddy, K. Whittington, S. Debic and J. DiRuggiero. 2021. Post-transcriptional regulation of redox homeostasis by the small RNA SHOxi in haloarchaea. RNA Biol. 31:1-15 PubMed PMID: 33522404.
Gelsinger, D. and J. DiRuggiero. 2018. Transcriptional landscape and regulatory roles of small non-coding RNAs in the oxidative stress response of the haloarchaeon Haloferax volcanii. J Bacteriol 200:e00779-17 PubMed PMID:29463600.
Microbial Ecology
Ertekin E., V. Meslier, A. Browning, J. Treadgold, and J. DiRuggiero. 2021. Functional and taxonomic diversity is driven by substrate architecture in endolithic communities from extreme environments. Env. Microbiol. 23: 3937–3956 PubMed PMID: 33078515.
Uritskiy G., A. Munn, M. Dailey, D.R. Gelsinger, S. Getsin, A. Davila, P. McCullough, J. Taylor and J. DiRuggiero. 2020. Environmental factors driving spatial heterogeneity in desert halophile microbial communities. Front. Microbiol. 11:578660 PubMed PMID: 33193201
Gelsinger D., G. Uritskiy, netbet casino reviewR. Reddy, A. Munn, K. Farney, and J. DiRuggiero. 2020. Regulatory non-coding small RNAs are diverse and abundant in an extremophilic microbial community. mSystems 5:e00584-19. PubMed PMID: 32019831.
View all publications [DiRuggiero Google Scholar]
Graduate Students
- Sadhana Chidambaran
- Frank Liu
- Lorna Mitchison-Field (rotation)
- Kevin Catalan
- Emma Dallon
Postdoctoral fellow
- Cesar Perez-Fernandez
Undergraduate Students
- Betty Huang
- Leo Busse
Assistant Research Scientist
- Bayleigh Murray